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April 23, 2020 Vol. 382 No. 17 | Internal Links | Dofollow |
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April 9, 2020 Vol. 382 No. 15 | Internal Links | Dofollow |
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Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19 H.R. Reynolds et al. | Internal Links | Dofollow |
Children with Covid-19 in Pediatric Emergency Departments in Italy N. Parri et al. | Internal Links | Dofollow |
Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19 G. Mancia et al. | Internal Links | Dofollow |
Early Detection of Covid-19 through a Citywide Pandemic Surveillance Platform H.Y. Chu et al. | Internal Links | Dofollow |
Physician Burnout, Interrupted P. Hartzband et al. | Internal Links | Dofollow |
Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19 M.R. Mehra et al. | Internal Links | Dofollow |
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Case 14-2020: A 37-Year-Old Man with Joint Pain and Eye Redness | Internal Links | Dofollow |
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http://nejm.org/doi/full/10.1056/NEJMoa2007621?query=featured_home | Internal Links | Dofollow |
Original Article | Internal Links | Dofollow |
Editorial Inhibitors of the Renin–Angiotensin–Aldosterone System and Covid-19 | Internal Links | Dofollow |
Editorial | Internal Links | Dofollow |
Loosening Covid-19 Restrictions E.J. Rubin, L.R. Baden, and S. Morrissey In this audio interview conducted on April 29, the editors discuss strategies to limit transmission of SARS-CoV-2 as restrictions are loosened and economies restart around the world. Apr 30 | Internal Links | Dofollow |
Renin–Angiotensin–Aldosterone System Blockers and Covid-19 G. Mancia and Others This population-based case–control study from northern Italy shows that the use of ACE inhibitors and ARBs was more frequent among patients with Covid-19 because of a higher prevalence of cardiovascular disease. However, there was no evidence that ACE inhibitors and ARBs affected the risk of Covid-19. May 01 | Internal Links | Dofollow |
RAAS Inhibitors and Risk of Covid-19 H.R. Reynolds and Others There is concern that patients taking renin–angiotensin–aldosterone system blockers have an increased risk of Covid-19, because angiotensin-converting enzyme 2 is a receptor for the virus. This study showed no increase in likelihood of a positive Covid-19 test or severe Covid-19 in patients taking any of five common classes of antihypertensive drugs. May 01 | Internal Links | Dofollow |
Correspondence | Internal Links | Dofollow |
Detection of Covid-19 through a Citywide Surveillance Platform H.Y. Chu and Others The Seattle Flu study, initiated in 2018, mailed kits for home collection of midnasal swabs to people reporting respiratory symptoms. From January 1 through March 9, 2020, specimens from 2,353 people were also tested for SARS-CoV-2; 25 (1.1%) tested positive. A specimen collected on February 24, 2020, was the first documented U.S. case of community transmission at the time. May 01 | Internal Links | Dofollow |
Perspective | Internal Links | Dofollow |
History in a Crisis — Lessons for Covid-19 D.S. Jones The history of human responses to epidemics carries various lessons for our current situation. Two of the more disheartening ones are that stigmatization follows closely on the heels of pathogens and that outbreaks too often claim the lives of health care providers. The article is accompanied by a slide show. Apr 30 | Internal Links | Dofollow |
Children with Covid-19 in Italy N. Parri, M. Lenge, and D. Buonsenso This letter describes a cohort of 100 children younger than 18 years of age with RT-PCR–confirmed Covid-19 who were assessed in 17 pediatric emergency departments in Italy. The descriptive results are compared with previously published results involving children in China and the United States. May 01 | Internal Links | Dofollow |
Physician Burnout, Interrupted P. Hartzband and J. Groopman The burnout problem won’t be solved without addressing the issues of autonomy, competence, and relatedness. During the Covid-19 pandemic, a sense of altruism and urgency has catalyzed restoration of these pillars of intrinsic motivation. Can these changes be sustained? May 01 | Internal Links | Dofollow |
Am I Part of the Cure or Am I Part of the Disease? C. Rose A front-line physician wonders how he can protect a vulnerable member of his household from the pathogens he’s exposed to in the ED — especially in a rapidly spreading pandemic of a novel virus and amid so many uncertainties. Apr 30 | Internal Links | Dofollow |
Image of the Week | Internal Links | Dofollow |
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http://nejm.org/doi/full/10.1056/NEJMoa1917537?query=featured_home | Internal Links | Dofollow |
Deep-Learning System to Identify Papilledema D. Milea and Others A deep-learning system that was applied to 14,341 fundus photographs differentiated optic disks with papilledema from normal disks with 96.4% sensitivity and 84.7% specificity in an external-testing data set. The prevalence of papilledema was 9.5%, yielding positive and negative predictive values of 39.8% and 99.6%, respectively. Apr 30 | Internal Links | Dofollow |
Editorial AI for the Eye — Automated Assistance for Clinicians Screening for Papilledema | Internal Links | Dofollow |
Anticoagulation with or without Clopidogrel after TAVI V.J. Nijenhuis and Others In a trial comparing the addition of clopidogrel with no clopidogrel in patients receiving anticoagulation, the incidence of any bleeding and of non–procedure-related bleeding was lower in the monotherapy group. Composite cardiovascular outcomes were noninferior for the monotherapy group but were superior only for a composite that included bleeding. Apr 30 | Internal Links | Dofollow |
Editorial How Un-POPular Is Bleeding in Patients with TAVI? | Internal Links | Dofollow |
Apixaban for Venous Thromboembolism in Cancer G. Agnelli and Others In a randomized trial, oral apixaban was noninferior to a low-molecular-weight heparin, dalteparin, in preventing recurrent venous thromboembolism at 6 months in patients with cancer. The use of apixaban was not associated with a higher risk of major bleeding than dalteparin, even in patients with gastrointestinal cancer. Apr 23 | Internal Links | Dofollow |
Editorial Anticoagulant Therapy for Venous Thromboembolism in Cancer | Internal Links | Dofollow |
Special Report | Internal Links | Dofollow |
RAAS Inhibitors in Patients with Covid-19 M. Vaduganathan and Others The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting enzyme 2 levels and activity in humans are uncertain. The authors hypothesize that ACE2 may be beneficial rather than harmful during lung injury and suggest that RAAS-inhibitor withdrawal may be harmful in some high-risk patients with known or suspected Covid-19. Apr 23 | Internal Links | Dofollow |
http://nejm.org/doi/full/10.1056/NEJMcpc1909623?query=featured_home | Internal Links | Dofollow |
Case Records of the Massachusetts General Hospital | Internal Links | Dofollow |
Clinical Implications of Basic Research | Internal Links | Dofollow |
Myocardial Infarcts, Stem Cells, and Inflammation J.A. Epstein, N. Rosenthal, and A.M. Feldman There has been much ado about the use of stem cells to replace cardiomyocytes after myocardial infarction. A recent study suggests that an immune response underlies benefit that had previously been attributed to stem cells. Apr 23 | Internal Links | Dofollow |
Review Article | Internal Links | Dofollow |
Ingestion of Caustic Substances R.S. Hoffman, M.M. Burns, and S. Gosselin Acids and alkalis can cause tissue damage on contact. Accidental and intentional ingestions of caustic materials in adults and children are a worldwide health issue. Acids act in part by denaturing proteins, and alkalis by saponifying fats. Approaches to management are outlined. Apr 30 | Internal Links | Dofollow |
Alpha1-Antitrypsin Deficiency P. Strnad, N.G. McElvaney, and D.A. Lomas AAT is a protease inhibitor targeting neutrophil elastase. It prevents the destruction of tissue, particularly in the lung, from elastase activity. AAT deficiency is a genetic disorder characterized by pulmonary disease, especially emphysema and bronchiectasis, and hepatic disease. Apr 09 | Internal Links | Dofollow |
Clinical and Social Risk Adjustment S.K. Agrawal and W.H. Shrank Adopting methods that account for all factors that influence patients’ risk, and those factors’ interdependence, could help create a more equitable health care payment system that better serves patients, including the most disadvantaged members of society. Apr 23 | Internal Links | Dofollow |
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Responding to Covid-19
B. Gates | Internal Links | Dofollow |
Virtually Perfect? Telemedicine for Covid-19
J.E. Hollander and B.G. Carr | Internal Links | Dofollow |
AI for the Eye — Automated Assistance for Clinicians Screening for Papilledema
I. Kohane | Internal Links | Dofollow |
How Un-POPular Is Bleeding in Patients with TAVI?
F. Feit | Internal Links | Dofollow |
History in a Crisis — Lessons for Covid-19
D.S. Jones | Internal Links | Dofollow |
Am I Part of the Cure or Am I Part of the Disease?
C. Rose | Internal Links | Dofollow |
Feeding Low-Income Children during the Pandemic
C.G. Dunn and Others | Internal Links | Dofollow |
Critical Supply Shortages
M.L. Ranney, V. Griffeth, and A.K. Jha | Internal Links | Dofollow |
Vitamin K1 Treatment Duration in Brodifacoum Poisoning | Internal Links | Dofollow |
Treatment for Pneumothorax | Internal Links | Dofollow |
Alcohol Abstinence in Drinkers with Atrial Fibrillation | Internal Links | Dofollow |
Tetravalent Dengue Vaccine in Healthy Children | Internal Links | Dofollow |
Effects of Intermittent Fasting on Health, Aging, and Disease | Internal Links | Dofollow |
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